Metabolic acidosis is characterized by a decrease in blood pH due to an increase in acidity, which typically occurs when the pH falls below the normal range. The normal blood pH range is approximately 7.35 to 7.45. When the pH drops to 7.35 or lower, it indicates an excess of hydrogen ions or a significant loss of bicarbonate, both of which are hallmarks of metabolic acidosis. This condition can arise from various factors, including kidney dysfunction, severe diarrhea, or diabetic ketoacidosis, and is clinically significant as it disrupts normal metabolic functions and can lead to serious health consequences if not addressed.
In contrast, the other pH ranges indicate either normal or alkalotic states, which do not correspond to metabolic acidosis. Understanding these pH levels is crucial for diagnosing and managing metabolic conditions effectively.