Which dietary factor can worsen insulin resistance?

High sugar intake is associated with an increase in insulin resistance due to several mechanisms. Consuming large amounts of sugar, particularly in the form of added sugars and refined carbohydrates, can lead to spikes in blood glucose levels. This situation prompts the pancreas to release more insulin to help regulate blood sugar. Over time, frequent high insulin levels can cause the body's cells to become less sensitive to insulin, thereby worsening insulin resistance.

Additionally, high sugar consumption is often linked to increased fat accumulation, particularly visceral fat, which is known to contribute to inflammation and further enhance insulin resistance. The presence of excess sugar in the diet can also promote fatty liver disease and other metabolic disorders that exacerbate insulin sensitivity issues.

In contrast, high protein intake, low carbohydrate intake, and high fat intake do not have the same direct detrimental effects on insulin sensitivity when consumed in moderation and as part of a balanced diet. Therefore, high sugar intake stands out as a significant dietary factor that can negatively impact insulin resistance.